Episode 121 originally aired December 30, 2018 to January 6, 2019
| Artist | Song | Album | |
| 1 | Rebecca Williams | Please Give Me A Match | Cat Scratchin' |
| 2 | Mary Jo Curry | Ooooo Weeee | May Jo Curry |
| 3 | JoAnne Shaw Taylor | Dyin' To Know | Wild |
| 4 | Michele D'Amour and The Love Dealers | Say What You Mean | Ante Up |
| 5 | Willa Vincitore | Demons | Better Days |
| 6 | Alice Stuart and the Formerlys | Freedom | Freedom |
| 7 | Rory Block | Black Mountain | A Woman's Soul, Tribute to Bessie Smith |
| 8 | Ruby and The Revelators | Cold, Cold Winter | Walk With Me |
| 9 | Bridget Kelly Band | Let Go | Blues Warrior |
| 10 | Koko Taylor | I Got What It Takes | I Got What It Takes |
| 11 | Suzie Vinnick | Watch Me | Shake The Love Around |
| 12 | Reloaded | Devil's Kiss | My Longest Mile |
| 13 | Teresa James and The Rhythm Tramps | Here in Babylon | Here in Babylon |
| 14 | Judy Brown | Free Range Man | Say It |
| 15 | Maria Muldaur | Get You Next To Me | Steady Love |
| 16 | Mindi Abair and The Boneshakers | Had To Learn The Hard Way | The East West Sessions |
| 17 | Shemekia Copeland | Such A Pretty Flame | America's Child |
| 18 | Cheryl Lescom & The Tucson Choir Boys | Guilty For Loving You | Cheryl Lescom & The Tucson Choir Boys |
| 19 | Gina Sicilia | Man In The Sky | Heard The Lie |
| 20 | Chris O | You Mine | Twisted Roots and Highways |
| 21 | Kaz Hawkins | I Just Want To Make Love To You | Feelin' Good |
| 22 | Renee Austin | Grateful | Songbirds & Angels |
| 23 | Rickie Lee Jones | The Last Chance Texaco | Rickie Lee Jones |
| 24 | Deb Ryder | Nothin' To Lose | Enjoy The Ride |
| 25 | Ilona Pal | Since My Baby Been Gone | - single - |
| 26 | Katie Webster | No Bread, No Meat | The Swamp Boogie Queen |
| 27 | Jamirae | Out of Reach | Gotta Find A Way |
| 28 | Libby Rae Watson | Big Joe | I Done Told Ya |
| 29 | KALO | One Mississippi | One |
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